Parametric geometry exploration of the human carotid artery bifurcation
نویسندگان
چکیده
منابع مشابه
Parametric geometry exploration of the human carotid artery bifurcation.
A parametric computational model of the human carotid artery bifurcation is employed to demonstrate that it is only necessary to simulate approximately one-half of a single heart pulse when performing a global exploration of the relationships between shear stress and changes in geometry. Using design of experiments and surface fitting techniques, a landscape is generated that graphically depict...
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Three-dimensional parametric computer aided design (CAD) geometry definitions of the human carotid artery bifurcation are presented for both Y-shaped and tuning-fork models. Drawing on methods largely developed in aerodynamic design, these parametric CAD geometries are deployed within a response surface methodology to systematically map the variation of spatially integrated mean shear stress wi...
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INTRODUCTION: Although well established correlations now exist between regions of reversed flow and sites of arterial disease [1], little evidence is available for methodologies that systematically compare how geometrical differences affect such relationships. Drawing on techniques developed in aerodynamic design, a parametric tuning-fork geometry model of the carotid artery bifurcation based o...
متن کاملFlow patterns in the human carotid artery bifurcation.
To elucidate the connection between blood flow and the localized genesis and development of atherosclerosis and thrombosis at the human carotid artery bifurcation, detailed studies of the flow patterns and distributions of fluid velocity and wall shear rate in this region were carried out using a transparent segment of the carotid artery, prepared from a human subject postmortem, and cinemicrog...
متن کاملAnatomical variations of the common carotid artery bifurcation.
BACKGROUND The correlation of the common carotid artery (CCA) bifurcation and its surrounding structures is poorly described. The aim of this study was to describe the anatomy of the CCA bifurcation relative to its surrounding structures. METHOD We dissected a total of 67 carotid specimens from 36 embalmed cadavers. CCA bifurcation occurred at the superior border of thyroid cartilage in 39% a...
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ژورنال
عنوان ژورنال: Journal of Biomechanics
سال: 2007
ISSN: 0021-9290
DOI: 10.1016/j.jbiomech.2006.11.002